Fibronectin in fulminant hepatic failure.
نویسندگان
چکیده
Thirteen out of 17 patients with fulminant hepatic failure had plasma fibronectin concentrations below the normal range (194--472 micrograms/ml), the mean concentration in all 17 patients being 117.9 +/- SE 19.4 micrograms/ml. There was a significant negative correlation between plasma fibronectin concentration and aspartate aminotransferase activity, suggesting that fibronectin is consumed during clearance of hepatocyte debris. The reduced availability of fibronectin may be an important factor in the impaired function of Kuppfer cells in patients with fulminant hepatic failure.
منابع مشابه
Acute fulminant hepatic failure due to colchicine – a rare manifestation of Gloriosa superba poisoning.
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ورودعنوان ژورنال:
- British medical journal
دوره 285 6350 شماره
صفحات -
تاریخ انتشار 1982